1. Dark, phlegmatic subjects ; or women with red hair and freckled complexion, especially at climaxis ; also broken-down constitutions.

2. Extreme alternations, mind and sensorium, (a) Mental activity with almost prophetic perception ; ecstasy ; loquacity with rapid change of subject especially when delirious ; hurry and flurry ; delusion of voices, etc. (b) Depression with anxiety ; patient silent, suspicious ; jealous ; weak memory, writing mistakes ; deranged time sense ; self-consciousness and selfishness.

3. Hyperaesthesia of the senses ; of body surface ; nervous intolerance of touch, pressure and constriction, even of clothing, especially about throat and abdomen.

4. Marked aggravation of all complaints from sleep ; patient sleeps into an attack ; sleep disturbed by frightful dreams, of dead and dying people, of suffocation, etc.

5. All distressing symptoms are > onset of discharges ; e.g. at menstrual period always > during flow.

6. Ailments left-sided or travel from left to right ; yet a special affinity for the appendix.

7. Adynamic fevers with low, muttering delirium ; face purplish, besotted-looking, dropped jaw ; offensive breath ; tremors especially of the tongue which is protruded with difficulty ; haemorrhages of dark, decomposed blood.

8. Septic states ; malignant ulcerations and suppuration ; with offensive discharges and bluish, livid appearance ; gangrene.

9. Tremors, cramps, spasms and even convulsions.

10. Modalities ; < heat especially heat of sun ; muggy weather ; must have air ; < spring ; throat symptoms < hot drinks and empty swallowing or liquids < than solids.

Note. The great trio of remedies for women at climaxis : Lachesis, Sepia and Sulphur.

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